Open position for a postdoctoral researcher in pain chronobiology at the University of Helsinki. The University of Helsinki is one of the leading universities in Nordics and Europe and an international scientific community of 40,000 students and researchers. Position of postdoctoral researcher is available at the Translational Pain Research group at Department of Physiology, Faculty of Medicine, led by Academy Research Fellow Dr. Vinko Palada. Dr. Palada´s team investigates circadian regulation of chronic pain and associated comorbidities by using the state-of-the-art methods such as high-throughput omics, molecular biology, drug library screens, characterization of the patient cohorts and the functional studies in experimental models. This is a new and exciting research field, with the goals to revolutionize our understanding of pain mechanisms and to develop new therapies for pain relief. The group closely collaborates with Helsinki University Hospital and Karolinska Institute, Sweden. The successful applicant has at least two first authorship publications and a doctoral degree in neuroscience, biology, chronobiology, pharmacology, sleep medicine or other related discipline. Deadline for application is May 9, 2024 and position will be filled as soon as possible.

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Post-doctoral position is available in the laboratory of Professor Jukka Westermarck at the Turku Bioscience Centre, University of Turku. Kinase inhibitors have become a mainstay in the cancer therapy, but their long-term efficacy is compromised by adaptive non-genetic drug-tolerance leading to drug resistance. We recently identified an oncogenic phosphatase DUSP6 as a central mediator of therapy tolerance development against HER2 targeted therapies in breast cancer. We also identified putative transcriptional regulators of therapy tolerance development, but what is the individual contribution of these transcription factors and can they be targeted in drug tolerant cancer cells is not yet understood. In order to address these biologically and clinically very relevant questions, we are looking for highly motivated post-doctoral fellow to join our dynamic research group broadly focused on phosphoproteome signalling in human cancers. The position will be filled upon identification of a suitable candidate and is available starting immediately thereafter (18.4.).