Faculty of Medicine, Jackson laboratory, invites applications for a Doctoral Researcher position in the field of mitochondrial signalling.
The focus of the lab is to unravel fundamental signalling mechanisms controlling mitochondrial function with a particular focus on mitochondrial translation. From this basic knowledge, we aim to exploit cell-type-specific susceptibilities to help devise novel treatments of diseases that stem from disregulated mitochondrial function. In this role the candidate will have the unique opportunity to drive an exciting project addressing models of mitochondrial dysfunction using genome-wide CRISPR screening. The successful candidate will have access to a wide range of methodologies with work consisting in preparation of cell models, construction of libraries, and analysis of metabolic, proteomic and microscopic data at the cellular and potentially physiological level.
We are looking for a highly motivated independent researcher with prime analytical skills driven by a passion for science. We expect you to formulate your own hypotheses, propose experimental design to address them, and take advantage of the laboratory and research community’s intellectual and skill resources to advance the knowledge of the field. The ideal candidate has an extensive background in standard molecular cell biological methods, ideally encompassing genetic and microscopic techniques and/or bioinformatics (analysis of large sequencing data). Expertise in biochemistry and molecular biology is a pre-requisite for this position. Additional expertise involving mammalian cell culture is highly desirable. The ideal candidate is an adaptable team-player, has excellent communication and organizational skills and a strong command in written and spoken English and should be familiar with the constraints related to translational research.
This position will provide multiple opportunities for collaborations with potential lab visits abroad and cross-disciplinary scientific exchange, where the candidate will receive extensive training in new technology. In return, the candidate is offered access to an extensive variety of methodology and cutting-edge techniques, appropriate supervision and help in career development.
More information about the lab including the latest research and news, can be found here: http://www.jacksonlab.org
The position is fully funded for three years starting from August 2023. The contract of employment includes a probationary period of 6 months. Salary will be based on the Universities salary scheme for teaching and research personnel composed of both task specific and personal performance components. The position will remain open until a suitable candidate is recruited.
Please submit: CV, list of publications, motivation letter including a description of your research interests, and the names of at least two referees.
For further information, please contact Christopher B. Jackson: christopher.jackson(at)helsinki.fi
Finland offers beautiful nature, secure social aspects and repeatedly ranks first on the World Happiness Report. The University of Helsinki as research-oriented university offers a stimulating and international environment. The Faculty of Medicine of the University of Helsinki, together with Helsinki University Central Hospital, The Helsinki Institute of Life Science, and the Institute for Molecular Medicine Finland forms the Academic Medical Center Helsinki. This medical campus ranks among the 10 best medical centers at European level and the 50 best centers in the world. More info on the Faculty or Medicine and AMCH can be found here: https://www.helsinki.fi/en/faculty-of-medicine